CFHR4 Antikörper (N-Term)

Produktnummer ABIN2776771

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CFHR4 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für CFHR4 Antikörper (N-Term) (ABIN2776771)

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFHR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CFHR4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FHR4 Antibody - N-terminal region

Sequenz: LWVSCANGQE VKPCDFPEIQ HGGLYYKSLR RLYFPAAAGQ SYSYYCDQNF

Homologie: Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FHR4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FHR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41371-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CFHR4

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Andere Bezeichnung: FHR4

Hintergrund:

Background Information: This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.

Gene Name: complement factor H

Alternative Symbols: FHR4, CFHL4, FHR-4

Protein Name: Complement factor H-related protein 4A EMBL CAG26679.2

Molekulargewicht: 63kDa

Gen-ID: 10877

NCBI Accession: NP_006675

UniProt: Q5DVJ7