ELAC2 Antikörper (C-Term)

Produktnummer ABIN2776757

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ELAC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Hund.

Kurzübersicht für ELAC2 Antikörper (C-Term) (ABIN2776757)

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ELAC2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ELAC2 Antibody - C-terminal region

Sequenz: ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT

Homologie: Dog: 100%, Human: 100%, Mouse: 83%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against ELAC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41346-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ELAC2

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Andere Bezeichnung: ELAC2

Hintergrund:

Background Information: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: elaC homolog 2 (E. coli)

Alternative Symbols: ELC2, HPC2, COXPD17

Protein Name: Zinc phosphodiesterase ELAC protein 2

Molekulargewicht: 55kDa

Gen-ID: 60528

UniProt: Q9BQ52