ELAC2 Antikörper (C-Term)

Produktnummer ABIN2776757

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ELAC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Hund.

Kurzübersicht für ELAC2 Antikörper (C-Term) (ABIN2776757)

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ELAC2 Antikörper

Bindungsspezifität: C-Term

Sequenz: ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT

Homologie: Dog: 100%, Human: 100%, Mouse: 83%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against ELAC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ELAC2

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Andere Bezeichnung: ELAC2

Hintergrund: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, XPO5, SNX5, ARIH1, TNPO3, WDR4, IPO7, TSN, SARS, PPP2CB, PFDN1, NRD1, HARS, FEN1, FOXH1, SMAD3, SMAD2, COPS5, ASCC2, NDUFA7, GOLM1, CUX1, PUF60,
Protein Size: 501

Molekulargewicht: 55 kDa

Gen-ID: 60528