WDR4 Antikörper (C-Term)

Produktnummer ABIN2776747

Der Kaninchen Polyklonal anti-WDR4 Antikörper (ABIN2776747) detektiert spezifisch WDR4 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Schwein und Saccharomyces cerevisiae.

Kurzübersicht für WDR4 Antikörper (C-Term) (ABIN2776747)

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-WDR4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: WDR4 Antibody - C-terminal region

Sequenz: AGADASFSSL YKATFDNVTS YLKKKEERLQ QQLEKKQRRR SPPPGPDGHA

Homologie: Cow: 93%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 90%, Rabbit: 83%, Rat: 75%, Yeast: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against WDR4. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115830

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu WDR4

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Andere Bezeichnung: WDR4

Hintergrund:

Targeted Subunit: WDR4

Background Information: WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: WD repeat domain 4

Alternative Symbols: hWH, Wuho, MIGSB, TRM82, GAMOS6, TRMT82

Protein Name: tRNA (guanine-N(7)-)-methyltransferase subunit WDR4

Molekulargewicht: 45kDa

Gen-ID: 10785

NCBI Accession: NP_387510

UniProt: P57081