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WDR4 Antikörper (C-Term)

Dieses Anti-WDR4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WDR4 in WB und IHC. Geeignet für Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Schwein und Saccharomyces cerevisiae.
Produktnummer ABIN2776747

Kurzübersicht für WDR4 Antikörper (C-Term) (ABIN2776747)

Target

Alle WDR4 Antikörper anzeigen
WDR4 (WD Repeat Domain 4 (WDR4))

Reaktivität

  • 31
  • 11
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Schwein, Saccharomyces cerevisiae

Wirt

  • 29
  • 2
Kaninchen

Klonalität

  • 27
  • 4
Polyklonal

Konjugat

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser WDR4 Antikörper ist unkonjugiert

Applikation

  • 23
  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    AGADASFSSL YKATFDNVTS YLKKKEERLQ QQLEKKQRRR SPPPGPDGHA

    Homologie

    Cow: 93%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 90%, Rabbit: 83%, Rat: 75%, Yeast: 75%

    Produktmerkmale

    This is a rabbit polyclonal antibody against WDR4. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 412 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    WDR4 (WD Repeat Domain 4 (WDR4))

    Andere Bezeichnung

    WDR4

    Hintergrund

    WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: TRM82
    Protein Interaction Partner: FAM118A, RABGGTB, METTL1, LGR4, CUL5, PDE12, WDR92, DCTPP1, P3H1, ELAC2, XPO5, NPLOC4, UBE2R2, DPP8, PPME1, ERO1L, UBQLN2, DBNL, KIAA1279, ARIH1, HSPBP1, PLIN3, ACTR2, SAE1, ASMTL, OGT, SURF2, SRP14, DNAJB1, DDX5, ALAD, ADSL, ERC1, UBP1, UBE2D1, TERF2, TE
    Protein Size: 412

    Molekulargewicht

    45 kDa

    Gen-ID

    10785

    NCBI Accession

    NM_033661, NP_387510

    UniProt

    P57081
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