WDR4 Antikörper (N-Term)

Produktnummer ABIN2776746

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WDR4 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für WDR4 Antikörper (N-Term) (ABIN2776746)

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WDR4 Antikörper

Bindungsspezifität: N-Term

Sequenz: FIYDCSAAEK KSQENKGEDA PLDQGSGAIL ASTFSKSGSY FALTDDSKRL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WDR4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WDR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 412 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WDR4

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Andere Bezeichnung: WDR4

Hintergrund: WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: TRM82
Protein Interaction Partner: FAM118A, RABGGTB, METTL1, LGR4, CUL5, PDE12, WDR92, DCTPP1, P3H1, ELAC2, XPO5, NPLOC4, UBE2R2, DPP8, PPME1, ERO1L, UBQLN2, DBNL, KIAA1279, ARIH1, HSPBP1, PLIN3, ACTR2, SAE1, ASMTL, OGT, SURF2, SRP14, DNAJB1, DDX5, ALAD, ADSL, ERC1, UBP1, UBE2D1, TERF2, TE
Protein Size: 412

Molekulargewicht: 45 kDa

Gen-ID: 10785

NCBI Accession: NM_018669, NP_061139

UniProt: P57081