Splicing Factor 1 Antikörper (C-Term)
Kurzübersicht für Splicing Factor 1 Antikörper (C-Term) (ABIN2776689)
Target
Alle Splicing Factor 1 (SF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- MASSTPLPWQ QNTTTTTTSA GTGSIPPWQQ QQAAAAASPG APQMQGNPTM
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Homologie
- Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SF1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human SF1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 639 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Splicing Factor 1 (SF1)
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Andere Bezeichnung
- SF1
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Hintergrund
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SF1 contains 1 KH domain and 1 CCHC-type zinc finger. It is necessary for the ATP-dependent first step of spliceosome assembly and binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. It may act as transcription repressor.
Alias Symbols: D11S636, ZFM1, ZNF162, BBP, MBBP
Protein Interaction Partner: KRTAP26-1, TRIM69, FAM168A, CIAO1, MKRN3, PSMA3, FUS, UBC, NEDD8, SUZ12, EED, RPL24, PLOD2, OSBP, NARS, GFPT1, GART, EIF4B, APBB1, SUPT5H, TROVE2, ITCH, PRPF40A, SAMHD1, XPO7, WBP4, FAF1, TCERG1, HSPH1, FARSB, GAS7, RANBP3, HIRIP3, HIST1H4A, XRCC5, U2AF2,
Protein Size: 639 -
Molekulargewicht
- 68 kDa
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Gen-ID
- 7536
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NCBI Accession
- NM_004630, NP_004621
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UniProt
- Q15637
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location
Target
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