ERI1 Antikörper (C-Term)

Produktnummer ABIN2776657

Dieses Anti-ERI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ERI1 in WB. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für ERI1 Antikörper (C-Term) (ABIN2776657)

Target: ERI1 (Exoribonuclease 1 (ERI1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERI1 Antikörper

Bindungsspezifität: C-Term

Sequenz: GSWDMSKFLN IQCQLSRLKY PPFAKKWINI RKSYGNFYKV PRSQTKLTIM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against THEX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human THEX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 349 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ERI1

Target: ERI1 (Exoribonuclease 1 (ERI1))

Andere Bezeichnung: THEX1

Hintergrund: THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Interaction Partner: UBC, HNRNPD, HHV8GK18_gp81, SLBP,
Protein Size: 349

Molekulargewicht: 38 kDa

Gen-ID: 90459

NCBI Accession: NM_153332, NP_699163

UniProt: Q8IV48