CELF6 Antikörper (Middle Region)

Produktnummer ABIN2776609

Der Kaninchen Polyklonal anti-CELF6 Antikörper (ABIN2776609) detektiert spezifisch CELF6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen und Kaninchen.

Kurzübersicht für CELF6 Antikörper (Middle Region) (ABIN2776609)

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CELF6 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: BRUNOL6 Antibody - middle region

Sequenz: QAALLAAAQG PGLGPVAAVA AQMQHVAAFS LVAAPLLPAA AANSPPGSGP

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BRUNOL6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41078-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CELF6

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Andere Bezeichnung: BRUNOL6

Hintergrund:

Background Information: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.

Gene Name: CUGBP, Elav-like family member 6

Alternative Symbols: BRUNOL6

Protein Name: CUGBP Elav-like family member 6

Molekulargewicht: 50kDa

Gen-ID: 60677

NCBI Accession: NP_443072

UniProt: Q96J87