CELF6 Antikörper (Middle Region)
-
- Target Alle CELF6 Antikörper anzeigen
- CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CELF6 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- QAALLAAAQG PGLGPVAAVA AQMQHVAAFS LVAAPLLPAA AANSPPGSGP
- Homologie
- Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against BRUNOL6. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL6
- Top Product
- Discover our top product CELF6 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 481 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))
- Andere Bezeichnung
- BRUNOL6 (CELF6 Produkte)
- Synonyme
- BRUNOL6 antikoerper, 6330569O16Rik antikoerper, Brunol6 antikoerper, CUGBP Elav-like family member 6 antikoerper, CUGBP, Elav-like family member 6 antikoerper, CELF6 antikoerper, Celf6 antikoerper
- Hintergrund
-
BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.
Alias Symbols: CELF6, BRUNOL6
Protein Size: 481 - Molekulargewicht
- 50 kDa
- Gen-ID
- 60677
- NCBI Accession
- NM_052840, NP_443072
- UniProt
- Q96J87
-