CELF6 Antikörper (Middle Region)

Produktnummer ABIN2776609

Dieses Anti-CELF6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CELF6 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen und Kaninchen.

Kurzübersicht für CELF6 Antikörper (Middle Region) (ABIN2776609)

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CELF6 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QAALLAAAQG PGLGPVAAVA AQMQHVAAFS LVAAPLLPAA AANSPPGSGP

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BRUNOL6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 481 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CELF6

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Andere Bezeichnung: BRUNOL6

Hintergrund: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.
Alias Symbols: CELF6, BRUNOL6
Protein Size: 481

Molekulargewicht: 50 kDa

Gen-ID: 60677

NCBI Accession: NM_052840, NP_443072

UniProt: Q96J87