BOLL Antikörper (N-Term)

Produktnummer ABIN2776601

Der Kaninchen Polyklonal anti-BOLL Antikörper wird verwendet zum Nachweis von BOLL in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für BOLL Antikörper (N-Term) (ABIN2776601)

Target: BOLL (Bol, Boule-Like (BOLL))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BOLL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BOLL Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: BOLL Antibody - N-terminal region

Sequenz: GGIDFKTNES DLRKFFSQYG SVKEVKIVND RAGVSKGYGF VTFETQEDAQ

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BOLL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BOLL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41065-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BOLL

Target: BOLL (Bol, Boule-Like (BOLL))

Andere Bezeichnung: BOLL

Hintergrund:

Background Information: This gene belongs to the DAZ gene family required for germ cell development. BOLL is an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Bol, boule-like (Drosophila)

Alternative Symbols: BOULE

Protein Name: Protein boule-like

Molekulargewicht: 31kDa

Gen-ID: 66037

NCBI Accession: NP_149019

UniProt: Q8N9W6