BOLL Antikörper (N-Term)

Produktnummer ABIN2776601

Der Kaninchen Polyklonal Anti-BOLL-Antikörper wurde für WB validiert. Er ist geeignet, BOLL in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd und Kaninchen zu detektieren.

Kurzübersicht für BOLL Antikörper (N-Term) (ABIN2776601)

Target: BOLL (Bol, Boule-Like (BOLL))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BOLL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BOLL Antikörper

Bindungsspezifität: N-Term

Sequenz: GGIDFKTNES DLRKFFSQYG SVKEVKIVND RAGVSKGYGF VTFETQEDAQ

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BOLL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BOLL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 283 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BOLL

Target: BOLL (Bol, Boule-Like (BOLL))

Andere Bezeichnung: BOLL

Hintergrund: This gene belongs to the DAZ gene family required for germ cell development. BOLL is an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: BOULE
Protein Interaction Partner: ZNF385C, HNRNPLL, C1orf94, RBFOX2, RBPMS, TFG, SERF2, NPBWR2, DAZ1, DAZ4,
Protein Size: 283

Molekulargewicht: 31 kDa

Gen-ID: 66037

NCBI Accession: NM_033030, NP_149019

UniProt: Q8N9W6