HNRNPAB Antikörper (C-Term)

Produktnummer ABIN2776585

Der Kaninchen Polyklonal Anti-HNRNPAB-Antikörper wurde für WB und IHC validiert. Er ist geeignet, HNRNPAB in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf und Zebrafisch (Danio rerio) zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für HNRNPAB Antikörper (C-Term) (ABIN2776585)

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNRNPAB Antikörper

Bindungsspezifität: C-Term

Sequenz: QQGYGPGYGG YDYSPYGYYG YGPGYDYSQG STNYGKSQRR GGHQNNYKPY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPAB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 332 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPAB Antikörper (ABIN2776585)

Taga, Miyoshi, Okajima, Matsuda, Nadano: "Identification of heterogeneous nuclear ribonucleoprotein A/B as a cytoplasmic mRNA-binding protein in early involution of the mouse mammary gland." in: Cell biochemistry and function, Vol. 28, Issue 4, pp. 321-8, (2010) (PubMed).

Bubenik, Ladd, Gerber, Budiman, Driscoll: "Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2." in: RNA biology, Vol. 6, Issue 1, pp. 73-83, (2009) (PubMed).

Details zu HNRNPAB

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Andere Bezeichnung: HNRPAB

Hintergrund: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ABBP1, HNRPAB
Protein Interaction Partner: UBC, SUMO2, IVNS1ABP, STAU1, DROSHA, MDM2, LIN28A, RPA3, RPA2, RPA1, ERG, RNF2, EZH2, EED, rev, YBX1, LDHB, TARDBP, HMGA1, USP19, PAN2, PTBP2, TP63, UBL4A, WHSC1, PTBP1, ITGA4, IL7R, IFIT3, IFIT2, FN1, SMURF1, ESR1, HNRNPA2B1, ATP6AP1, MRPS25, MRPS7, MRPS
Protein Size: 332

Molekulargewicht: 37 kDa

Gen-ID: 3182

NCBI Accession: NM_031266, NP_112556