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PIGZ Antikörper (N-Term)

PIGZ Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776579
  • Target Alle PIGZ Antikörper anzeigen
    PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
    Bindungsspezifität
    • 5
    • 1
    N-Term
    Reaktivität
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 4
    • 2
    • 1
    • 1
    Dieser PIGZ Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    VLWGGLSLLR VLWCLLPQTG YVHPDEFFQS PEVMAEDILG VQAARPWEFY
    Homologie
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 80%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PIGZ. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PIGZ
    Top Product
    Discover our top product PIGZ Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 579 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Taron, Colussi, Wiedman, Orlean, Taron: "Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36083-92, (2004) (PubMed).

  • Target
    PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
    Andere Bezeichnung
    PIGZ (PIGZ Produkte)
    Synonyme
    F630022B06Rik antikoerper, GPI-MT-IV antikoerper, PIG-Z antikoerper, SMP3 antikoerper, phosphatidylinositol glycan anchor biosynthesis, class Z antikoerper, phosphatidylinositol glycan anchor biosynthesis class Z antikoerper, Pigz antikoerper, PIGZ antikoerper
    Hintergrund
    The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
    Alias Symbols: FLJ12768, GPI-MT-IV, MGC52163, SMP3, PIG-Z
    Protein Size: 579
    Molekulargewicht
    63 kDa
    Gen-ID
    80235
    NCBI Accession
    NM_025163, NP_079439
    UniProt
    Q86VD9
    Pathways
    Inositol Metabolic Process
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