PIGZ Antikörper (N-Term)

Produktnummer ABIN2776579

Dieser Anti-PIGZ Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PIGZ in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Saccharomyces cerevisiae. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für PIGZ Antikörper (N-Term) (ABIN2776579)

Target: PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIGZ Antikörper

Bindungsspezifität: N-Term

Sequenz: VLWGGLSLLR VLWCLLPQTG YVHPDEFFQS PEVMAEDILG VQAARPWEFY

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against PIGZ. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGZ

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 579 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIGZ Antikörper (ABIN2776579)

Taron, Colussi, Wiedman, Orlean, Taron: "Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36083-92, (2004) (PubMed).

Details zu PIGZ

Target: PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))

Andere Bezeichnung: PIGZ

Hintergrund: The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
Alias Symbols: FLJ12768, GPI-MT-IV, MGC52163, SMP3, PIG-Z
Protein Size: 579

Molekulargewicht: 63 kDa

Gen-ID: 80235

NCBI Accession: NM_025163, NP_079439

UniProt: Q86VD9

Pathways: Inositol Metabolic Process