PAPOLG Antikörper (Middle Region)

Produktnummer ABIN2776560

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAPOLG in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für PAPOLG Antikörper (Middle Region) (ABIN2776560)

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPOLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAPOLG Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PAPOLG Antibody - middle region

Sequenz: SVDAIGGESM PIPTIDTSRK KRLPSKELPD SSSPVPANNI RVIKNSIRLT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PAPOLG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAPOLG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40991-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PAPOLG

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Andere Bezeichnung: PAPOLG

Hintergrund:

Background Information: PAPOLG is a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60 % identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity.This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60 % identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14.

Gene Name: Poly(A) polymerase gamma

Alternative Symbols: FLJ11805, FLJ12972, FLJ13482, FLJ14187, MGC133307, MGC133308

Protein Name: Poly(A) polymerase gamma

Molekulargewicht: 83kDa

Gen-ID: 64895

NCBI Accession: NP_075045

UniProt: Q9BWT3