SSX4 Antikörper (N-Term)

Produktnummer ABIN2776445

Der Kaninchen Polyklonal anti-SSX4 Antikörper wird verwendet zum Nachweis von SSX4 in Proben von Human und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für SSX4 Antikörper (N-Term) (ABIN2776445)

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SSX4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SSX4 Antibody - N-terminal region

Sequenz: NGDDAFARRP RDDAQISEKL RKAFDDIAKY FSKKEWEKMK SSEKIVYVYM

Homologie: Cow: 83%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SSX4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35782-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SSX4

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Andere Bezeichnung: SSX4

Hintergrund:

Background Information: SSX4 belongs to the SSX family. It contains 1 KRAB-related domain.SSX4 could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Synovial sarcoma, X breakpoint 4

Alternative Symbols: CT5.4

Protein Name: Protein SSX4

Molekulargewicht: 22kDa

Gen-ID: 6759

NCBI Accession: NP_005627

UniProt: O60224