MAGEA9 Antikörper (Middle Region)

Produktnummer ABIN2776439

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAGEA9 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein und Saccharomyces cerevisiae.

Kurzübersicht für MAGEA9 Antikörper (Middle Region) (ABIN2776439)

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Reaktivität: Human, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAGEA9 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: MAGEA9 Antibody - middle region

Sequenz: ALKLKVAELV HFLLHKYRVK EPVTKAEMLE SVIKNYKRYF PVIFGKASEF

Homologie: Cow: 77%, Dog: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rabbit: 85%, Rat: 85%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MAGEA9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35768-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MAGEA9

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Andere Bezeichnung: MAGEA9

Hintergrund:

Background Information: MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Gene Name: Melanoma antigen family A, 9

Alternative Symbols: CT1.9, MAGE9

Protein Name: Melanoma-associated antigen 9

Molekulargewicht: 35kDa

Gen-ID: 4108

NCBI Accession: NP_005356

UniProt: P43362