TCEAL1 Antikörper (Middle Region)

Produktnummer ABIN2776430

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-TCEAL1 Antikörper wird verwendet zum Nachweis von TCEAL1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für TCEAL1 Antikörper (Middle Region) (ABIN2776430)

Target: TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TCEAL1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR

Homologie: Cow: 87%, Dog: 87%, Horse: 87%, Human: 87%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against TCEAL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TCEAL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 159 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TCEAL1 Antikörper (ABIN2776430)

Klos, Wyszomierski, Sun, Tan, Zhou, Li, Yang, Yin, Hittelman, Yu: "ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells." in: Cancer research, Vol. 66, Issue 4, pp. 2028-37, (2006) (PubMed).

Details zu TCEAL1

Target: TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))

Andere Bezeichnung: TCEAL1

Hintergrund: TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) protein family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.
Alias Symbols: SIIR, p21, pp21
Protein Interaction Partner: MAPK14, DYRK1B, UBC, HOXB6, USP11, TCEAL2, TCEAL4, FEM1C, PPP2R2D, KDM3A, FEM1A, TIPIN, PDCD5, GMPS, CUL2, USP7, TCEB1, RFC1, HSPA4L, SSR3, PPP2R2A,
Protein Size: 159

Molekulargewicht: 19 kDa

Gen-ID: 9338

NCBI Accession: NM_001006640, NP_001006641

UniProt: Q15170