TRIP13 Antikörper (N-Term)
Kurzübersicht für TRIP13 Antikörper (N-Term) (ABIN2776416)
Target
Alle TRIP13 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- KDSQPIDLSA CTVALHIFQL NEDGPSSENL EEETENIIAA NHWVLPAAEF
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Homologie
- Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TRIP13. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIP13
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 432 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
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Andere Bezeichnung
- TRIP13
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Hintergrund
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The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
Alias Symbols: 16E1BP
Protein Interaction Partner: KRTAP26-1, KRTAP12-1, KRTAP12-2, MORN3, TEX37, METTL15, MGAT5B, C4orf33, GLYCTK, M1AP, LRR1, LNX1, RHOXF2, LOXL4, ZNF34, FNDC3B, TINAGL1, PBLD, SEMA4G, SPRYD7, PELI1, PLSCR3, PCMTD2, CYB5R2, AMDHD2, TNRC6A, DIP2A, DPYSL4, TRIP13, SIGLEC5, TPT1, SCP2, QARS
Protein Size: 432 -
Molekulargewicht
- 49 kDa
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Gen-ID
- 9319
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NCBI Accession
- NM_004237, NP_004228
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UniProt
- Q15645
Target
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