EDF1 Antikörper (N-Term)

Produktnummer ABIN2776405

Der Kaninchen Polyklonal Anti-EDF1 Antikörper wurde für WB und IF validiert. Er ist geeignet, EDF1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio) zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für EDF1 Antikörper (N-Term) (ABIN2776405)

Target: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-EDF1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAESDWDTVT VLRKKGPTAA QAKSKQAILA AQRRGEDVET SKKWAAGQNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EDF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 148 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EDF1 Antikörper (ABIN2776405)

Leidi, Mariotti, Maier: "The effects of silencing EDF-1 in human endothelial cells." in: Atherosclerosis, Vol. 211, Issue 1, pp. 55-60, (2010) (PubMed).

Leidi, Mariotti, Maier: "EDF-1 contributes to the regulation of nitric oxide release in VEGF-treated human endothelial cells." in: European journal of cell biology, Vol. 89, Issue 9, pp. 654-60, (2010) (PubMed).

Leidi, Mariotti, Maier: "Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 16, pp. 2733-42, (2009) (PubMed).

Details zu EDF1

Target: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Andere Bezeichnung: EDF1

Hintergrund: EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the tran
Alias Symbols: EDF-1, MBF1, MGC9058
Protein Interaction Partner: MEOX2, UBC, IDH3G, UBE2I, MAPK6, NRL, JUN, CEBPA, NR1H3, NR5A2, PPARG, TBP, TAF1, NR5A1, RXRA, PRKCA, ATF2, CREB1, ATF1, CALM3, CALM1,
Protein Size: 148

Molekulargewicht: 16 kDa

Gen-ID: 8721

NCBI Accession: NM_003792, NP_003783

UniProt: O60869