EDF1 Antikörper (N-Term)

Produktnummer ABIN2776405

Der Kaninchen Polyklonal Anti-EDF1-Antikörper wurde für WB und IF validiert. Er ist geeignet, EDF1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio) zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für EDF1 Antikörper (N-Term) (ABIN2776405)

Target: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-EDF1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAESDWDTVT VLRKKGPTAA QAKSKQAILA AQRRGEDVET SKKWAAGQNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EDF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 148 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EDF1 Antikörper (ABIN2776405)

Leidi, Mariotti, Maier: "The effects of silencing EDF-1 in human endothelial cells." in: Atherosclerosis, Vol. 211, Issue 1, pp. 55-60, (2010) (PubMed).

Leidi, Mariotti, Maier: "EDF-1 contributes to the regulation of nitric oxide release in VEGF-treated human endothelial cells." in: European journal of cell biology, Vol. 89, Issue 9, pp. 654-60, (2010) (PubMed).

Leidi, Mariotti, Maier: "Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 16, pp. 2733-42, (2009) (PubMed).

Details zu EDF1

Target: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Andere Bezeichnung: EDF1

Hintergrund: EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the tran
Alias Symbols: EDF-1, MBF1, MGC9058
Protein Interaction Partner: MEOX2, UBC, IDH3G, UBE2I, MAPK6, NRL, JUN, CEBPA, NR1H3, NR5A2, PPARG, TBP, TAF1, NR5A1, RXRA, PRKCA, ATF2, CREB1, ATF1, CALM3, CALM1,
Protein Size: 148

Molekulargewicht: 16 kDa

Gen-ID: 8721

NCBI Accession: NM_003792, NP_003783

UniProt: O60869