SMPD1 Antikörper (Middle Region)
Kurzübersicht für SMPD1 Antikörper (Middle Region) (ABIN2776371)
Target
Alle SMPD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- INSTDPAGQL QWLVGELQAA EDRGDKVHII GHIPPGHCLK SWSWNYYRIV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%, Sheep: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SMPD1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SMPD1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 631 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
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Andere Bezeichnung
- SMPD1
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Hintergrund
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SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB).
Alias Symbols: ASM, NPD, ASMASE
Protein Interaction Partner: ELAVL1, DUSP23, NR1H2, ANXA7, ANXA4, NGFRAP1, ASAH1,
Protein Size: 631 -
Molekulargewicht
- 65 kDa
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Gen-ID
- 6609
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NCBI Accession
- NM_000543, NP_000534
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UniProt
- P17405
Target
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