GABRQ Antikörper (N-Term)

Produktnummer ABIN183150

Dieser Anti-GABRQ Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GABRQ in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für GABRQ Antikörper (N-Term) (ABIN183150)

Target: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GABRQ Antikörper

Bindungsspezifität: N-Term

Sequenz: KFHFEFSSAV PEVVLNLFNC KNCANEAVVQ KILDRVLSRY DVRLRPNFGG

Homologie: Cow: 87%, Dog: 87%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GABRQ. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRQ

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 632 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GABRQ Antikörper (ABIN183150)

Fatemi, Folsom, Rooney, Thuras: "mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway." in: Translational psychiatry, Vol. 3, pp. e271, (2013) (PubMed).

Details zu GABRQ

Target: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Andere Bezeichnung: GABRQ

Hintergrund: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
Alias Symbols: THETA
Protein Size: 632

Molekulargewicht: 72 kDa

Gen-ID: 55879

NCBI Accession: NM_018558, NP_061028

UniProt: Q9UN88