CLCA2 Antikörper (C-Term)

Produktnummer ABIN2776187

Der Kaninchen Polyklonal anti-CLCA2 Antikörper wird verwendet zum Nachweis von CLCA2 in Proben von Human, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen und Ratte. Er wurde validiert für WB.

Kurzübersicht für CLCA2 Antikörper (C-Term) (ABIN2776187)

Target: CLCA2 (Chloride Channel Accessory 2 (CLCA2))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CLCA2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CLCA2 Antibody - C-terminal region

Sequenz: RYFFSFAANG RYSLKVHVNH SPSISTPAHS IPGSHAMYVP GYTANGNIQM

Homologie: Cow: 100%, Dog: 85%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 77%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CLCA2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLCA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35195-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CLCA2

Target: CLCA2 (Chloride Channel Accessory 2 (CLCA2))

Andere Bezeichnung: CLCA2

Hintergrund:

Background Information: The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.

Gene Name: Chloride channel accessory 2

Alternative Symbols: CACC, CACC3, CLCRG2, CaCC-3

Protein Name: Calcium-activated chloride channel regulator 2

Molekulargewicht: 104 kDa

Gen-ID: 9635

NCBI Accession: NP_006527

UniProt: Q9UQC9