CLCNKB Antikörper (C-Term)
Kurzübersicht für CLCNKB Antikörper (C-Term) (ABIN2776083)
Target
Alle CLCNKB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- ILAAGCPTEP VTLKLSPETS LHEAHNLFEL LNLHSLFVTS RGRAVGCVSW
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Homologie
- Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CLCNKB. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLCNKB
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 687 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CLCNKB (Chloride Channel Kb (CLCNKB))
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Andere Bezeichnung
- CLCNKB
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Hintergrund
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Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Alias Symbols: CLCKB, ClC-K2, ClC-Kb, hClC-Kb
Protein Interaction Partner: Dlg4,
Protein Size: 687 -
Molekulargewicht
- 76 kDa
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Gen-ID
- 1188
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NCBI Accession
- NM_000085, NP_000076
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UniProt
- P51801
Target
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