CLCNKB Antikörper (N-Term)

Produktnummer ABIN2776082

Der Kaninchen Polyklonal anti-CLCNKB Antikörper wird verwendet zum Nachweis von CLCNKB in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für CLCNKB Antikörper (N-Term) (ABIN2776082)

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCNKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CLCNKB Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CLCNKB Antibody - N-terminal region

Sequenz: MEEFVGLREG SSGNPVTLQE LWGPCPRIRR GIRGGLEWLK QKLFRLGEDW

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CLCNKB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLCNKB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096917

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CLCNKB

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Andere Bezeichnung: CLCNKB

Hintergrund:

Background Information: Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

Gene Name: Chloride channel, voltage-sensitive Kb

Alternative Symbols: CLCKB, ClC-K2, ClC-Kb

Protein Name: CLCNKB protein EMBL AAH20873.1

Molekulargewicht: 50kDa

Gen-ID: 1188

UniProt: Q8WW53