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DMP1 Antikörper (Middle Region)

This anti-DMP1 antibody (ABIN2776044) is a Rabbit Polyclonal antibody detecting DMP1 in WB. Suitable for Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow, Pig.
Produktnummer ABIN2776044

Quick Overview for DMP1 Antikörper (Middle Region) (ABIN2776044)

Target

Alle DMP1 (DMTF1) Antikörper anzeigen
DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Reaktivität

  • 81
  • 18
  • 18
  • 7
  • 7
  • 7
  • 6
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Schwein

Wirt

  • 70
  • 8
  • 3
  • 1
Kaninchen

Klonalität

  • 75
  • 7
Polyklonal

Konjugat

  • 36
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DMP1 Antikörper ist unkonjugiert

Applikation

  • 56
  • 33
  • 26
  • 26
  • 8
  • 6
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 15
    • 8
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against DMTF1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human DMTF1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 760 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

    Andere Bezeichnung

    DMTF1

    Hintergrund

    DMTF1 is a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. DMTF1 is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of DMTF1 is regulated by binding of D-cyclins. The gene encoding DMTF1 is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer.
    Alias Symbols: DMP1, DMTF, FLJ41265, hDMP1
    Protein Interaction Partner: SRA1, TP53, ATF7IP, CCND1, CCND3, CCND2,
    Protein Size: 760

    Molekulargewicht

    84 kDa

    Gen-ID

    9988

    NCBI Accession

    NM_021145, NP_066968

    UniProt

    Q9Y222
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