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RFX6 Antikörper (Middle Region)

This anti-RFX6 antibody (ABIN2776023) is a Rabbit Polyclonal antibody detecting RFX6 in WB. Suitable for Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio).
Produktnummer ABIN2776023

Kurzübersicht für RFX6 Antikörper (Middle Region) (ABIN2776023)

Target

Alle RFX6 Antikörper anzeigen
RFX6 (Regulatory Factor X 6 (RFX6))

Reaktivität

  • 19
  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Zebrafisch (Danio rerio)

Wirt

  • 17
  • 2
Kaninchen

Klonalität

  • 19
Polyklonal

Konjugat

  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RFX6 Antikörper ist unkonjugiert

Applikation

  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 4
    • 1
    • 1
    Middle Region

    Sequenz

    LGTRGHSKYH YYGIGIKESS AYYHSVYSGK GLTRFSGSKL KNEGGFTRKY

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against Rfx6. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of MOUSE Rfx6
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    RFX6 (Regulatory Factor X 6 (RFX6))

    Andere Bezeichnung

    Rfx6

    Hintergrund

    Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.
    Protein Size: 524

    Molekulargewicht

    57 kDa

    Gen-ID

    320995

    Pathways

    Carbohydrate Homeostasis
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