Forkhead Box K2 Antikörper (Middle Region)

Produktnummer ABIN2776014

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Forkhead Box K2 Antikörper wird verwendet zum Nachweis von Forkhead Box K2 in Proben von Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Schwein und Hund. Er wurde validiert für WB und IHC.

Kurzübersicht für Forkhead Box K2 Antikörper (Middle Region) (ABIN2776014)

Target: Forkhead Box K2 (FOXK2)

Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Forkhead Box K2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Forkhead Box K2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: FOXK2 Antibody - middle region

Sequenz: ANTYTVSGQA VVTPAAVLAP PKAEAQENGD HREVKVKVEP IPAIGHATLG

Homologie: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 79%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXK2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100889

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Forkhead Box K2 Antikörper (ABIN2776014)

Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

Details zu Forkhead Box K2

Target: Forkhead Box K2 (FOXK2)

Andere Bezeichnung: FOXK2

Hintergrund:

Background Information: FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Forkhead box K2

Alternative Symbols: ILF, ILF1, ILF-1, nGTBP

Protein Name: Forkhead box protein K2

Molekulargewicht: 69kDa

Gen-ID: 3607

NCBI Accession: NP_004505

UniProt: Q01167