Forkhead Box K2 Antikörper (Middle Region)

Produktnummer ABIN2776014

Der Kaninchen Polyklonal Anti-Forkhead Box K2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Forkhead Box K2 in Proben von Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Schwein und Hund zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Forkhead Box K2 Antikörper (Middle Region) (ABIN2776014)

Target: Forkhead Box K2 (FOXK2)

Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Forkhead Box K2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Forkhead Box K2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ANTYTVSGQA VVTPAAVLAP PKAEAQENGD HREVKVKVEP IPAIGHATLG

Homologie: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 79%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXK2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 660 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Forkhead Box K2 Antikörper (ABIN2776014)

Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

Details zu Forkhead Box K2

Target: Forkhead Box K2 (FOXK2)

Andere Bezeichnung: FOXK2

Hintergrund: FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: ILF, ILF-1, ILF1
Protein Interaction Partner: HECW2, SOX2, CBX6, SUMO2, BAP1, IRF2, AMOT, IL2,
Protein Size: 660

Molekulargewicht: 69 kDa

Gen-ID: 3607

NCBI Accession: NM_004514, NP_004505

UniProt: Q01167