TRIOBP Antikörper (Middle Region)

Produktnummer ABIN2775973

Der Kaninchen Polyklonal Anti-TRIOBP-Antikörper wurde für WB und IHC validiert. Er ist geeignet, TRIOBP in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Hund und Schwein zu detektieren.

Kurzübersicht für TRIOBP Antikörper (Middle Region) (ABIN2775973)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIOBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TRIOBP Antikörper

Bindungsspezifität: Middle Region

Sequenz: QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 431 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Andere Bezeichnung: TRIOBP

Hintergrund: TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
Protein Size: 431

Molekulargewicht: 47 kDa

Gen-ID: 11078

NCBI Accession: NM_138632, NP_619538

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization