CREB3L2 Antikörper (N-Term)

Produktnummer ABIN2775946

Dieses Anti-CREB3L2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CREB3L2 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für CREB3L2 Antikörper (N-Term) (ABIN2775946)

Target: CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREB3L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CREB3L2 Antikörper

Bindungsspezifität: N-Term

Sequenz: HSYSLCEEPR AQSPFTHITS DSFNDDEVES EKWYLSTDF

Homologie: Cow: 93%, Dog: 85%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 86%, Rabbit: 87%, Rat: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against CREB3L2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREB3L2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CREB3L2 Antikörper (ABIN2775946)

Lynch, Maillet, Vanhoutte, Schloemer, Sargent, Blair, Lynch, Okada, Aronow, Osinska, Prywes, Lorenz, Mori, Lawler, Robbins, Molkentin: "A thrombospondin-dependent pathway for a protective ER stress response." in: Cell, Vol. 149, Issue 6, pp. 1257-68, (2012) (PubMed).

Fox, Hanlon, Andrew: "The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity." in: The Journal of cell biology, Vol. 191, Issue 3, pp. 479-92, (2010) (PubMed).

Sievert, Jackson, Gai, Hakonarson, Judkins, Resnick, Sutton, Storm, Shaikh, Biegel: "Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene." in: Brain pathology (Zurich, Switzerland), Vol. 19, Issue 3, pp. 449-58, (2009) (PubMed).

Storlazzi, Mertens, Nascimento, Isaksson, Wejde, Brosjo, Mandahl, Panagopoulos: "Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma." in: Human molecular genetics, Vol. 12, Issue 18, pp. 2349-58, (2003) (PubMed).

Details zu CREB3L2

Target: CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))

Andere Bezeichnung: CREB3L2

Hintergrund: CREB3L2 is a member of the old astrocyte specifically induced substance (OASIS) DNA binding and basic leucine zipper dimerization (bZIP) family of transcription factors, which includes CREB3 (MIM 606443) and CREB4 (MIM 607138).
Alias Symbols: BBF2H7
Protein Interaction Partner: Fbxw7, UBE2D3, UBA1, GAS7, UBC, GCFC2, RGS16, PXN, CEP19, GULP1, RND1, ZNF212, PTP4A1, ELAVL1, SUMO2, Dynll1,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 64764

NCBI Accession: NM_194071, NP_919047

UniProt: Q70SY1

Pathways: Thyroid Hormone Synthesis