SUV420H1 Antikörper (Middle Region)

Produktnummer ABIN2775877

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-SUV420H1 Antikörper (ABIN2775877) detektiert spezifisch SUV420H1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen und Pferd.

Kurzübersicht für SUV420H1 Antikörper (Middle Region) (ABIN2775877)

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUV420H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SUV420H1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: KMT5B Antibody - middle region

Sequenz: NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESR

Homologie: Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUV420H1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUV420H1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34567-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SUV420H1 Antikörper (ABIN2775877)

Murata, Kondo, Sugimoto, Kawashima, Saito, Isomura, Kanda, Tsurumi: "Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells." in: Journal of virology, Vol. 86, Issue 9, pp. 4752-61, (2012) (PubMed).

Gatta, Mantovani: "NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations." in: Nucleic acids research, Vol. 36, Issue 20, pp. 6592-607, (2008) (PubMed).

Twells, Metzker, Brown, Cox, Garey, Hammond, Hey, Levy, Nakagawa, Philips, Todd, Hess: "The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13." in: Genomics, Vol. 72, Issue 3, pp. 231-42, (2001) (PubMed).

Details zu SUV420H1

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Andere Bezeichnung: KMT5B

Hintergrund:

Background Information: This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: lysine methyltransferase 5B

Alternative Symbols: CGI85, MRD51, CGI-85, SUV420H1

Protein Name: histone-lysine N-methyltransferase KMT5B

Molekulargewicht: 99 kDa

Gen-ID: 51111

UniProt: Q4FZB7