TAF9 Antikörper (N-Term)
Kurzübersicht für TAF9 Antikörper (N-Term) (ABIN2775865)
Target
Alle TAF9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- GLKYINVGDL AREEQLYDGY DEEYDCPILD EDRVVDELDN QMREGGVIVD
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Homologie
- Cow: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 90%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TAF9. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TAF9
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 169 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TAF9 (RNA Polymerase II TBP-Associated Factor Subunit G (TAF9))
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Andere Bezeichnung
- TAF9
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Hintergrund
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16.
Alias Symbols: AK6, CIP, CINAP, TAF2G, AD-004, hCINAP, CGI-137, TAFII31, TAFII32, MGC:1603, MGC:3647, MGC:5067, TAFIID32
Protein Interaction Partner: TAF6L, DRAP1, LAMTOR5, NDRG1, RPS14, KPNA1, UBC, TBCA, NCOA2, FEZ1, RPS24, ANK2, HNF4A, GALNT6, MED26, KAT2B, HIST3H3, FBLN1, COIL, AHR, TAF1L, TAF9B, TBP, TAF13, TAF10, TAF7, TAF6, TAF5, TAF4, TAF2, FKBP4, FBL, DHX8, APP, CIITA, RNF138, KPNA6, UBA1, ALL1
Protein Size: 169 -
Molekulargewicht
- 19 kDa
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Gen-ID
- 6880
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NCBI Accession
- NM_001015891, NP_001015891
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UniProt
- Q9Y3D8
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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