FHL2 Antikörper (C-Term)

Produktnummer ABIN2775839

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FHL2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für FHL2 Antikörper (C-Term) (ABIN2775839)

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FHL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FHL2 Antikörper

Bindungsspezifität: C-Term

Sequenz: RFTARDDFAY CLNCFCDLYA KKCAGCTNPI SGLGGTKYIS FEERQWHNDC

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against FHL2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FHL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 279 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FHL2 Antikörper (ABIN2775839)

Han, Wu, Zhao, Meng, Si, Yang, Fu, Yu: "FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells." in: Nucleic acids research, Vol. 37, Issue 12, pp. 3996-4009, (2009) (PubMed).

Saeki, Endo, Ide, Nagashima, Yumoto, Toyoda, Suzuki, Hayashizaki, Sakaki, Okada-Hatakeyama: "Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells." in: BMC genomics, Vol. 10, pp. 545, (2009) (PubMed).

Lee, Chung, Kang: "Combined treatment of high pressure and heat on killing spores of Alicyclobacillus acidoterrestris in apple juice concentrate." in: Journal of food protection, Vol. 69, Issue 5, pp. 1056-60, (2006) (PubMed).

Details zu FHL2

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Andere Bezeichnung: FHL2

Hintergrund: FHL2 is a member of LIM proteins that contain a highly conserved double zinc finger motif called the LIM domain.
Alias Symbols: DRAL, AAG11, FHL-2, SLIM3, SLIM-3
Protein Interaction Partner: SP2, RFX3, REL, NRF1, JUP, INCA1, FAM154A, ZNF417, FAM129A, GLYR1, CCDC92, ARHGAP9, KIAA1217, GNG12, DCP1A, ZFP64, BANP, KANK2, RAI2, ZMYM4, BLZF1, ZNF131, CSN2, SIGLEC6, DTX2, TRIM63, TRIM55, FOXO1, SUMO2, PTCH1, DCTN3, HEXIM1, ERP44, SMAD4, SMAD3, SMAD2
Protein Size: 279

Molekulargewicht: 32 kDa

Gen-ID: 2274

NCBI Accession: NM_201555, NP_963849

UniProt: Q14192

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha