FHL2 Antikörper (C-Term)

Produktnummer ABIN2775839

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FHL2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für FHL2 Antikörper (C-Term) (ABIN2775839)

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FHL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FHL2 Antikörper

Bindungsspezifität: C-Term

Sequenz: RFTARDDFAY CLNCFCDLYA KKCAGCTNPI SGLGGTKYIS FEERQWHNDC

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against FHL2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FHL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 279 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FHL2 Antikörper (ABIN2775839)

Han, Wu, Zhao, Meng, Si, Yang, Fu, Yu: "FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells." in: Nucleic acids research, Vol. 37, Issue 12, pp. 3996-4009, (2009) (PubMed).

Saeki, Endo, Ide, Nagashima, Yumoto, Toyoda, Suzuki, Hayashizaki, Sakaki, Okada-Hatakeyama: "Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells." in: BMC genomics, Vol. 10, pp. 545, (2009) (PubMed).

Lee, Chung, Kang: "Combined treatment of high pressure and heat on killing spores of Alicyclobacillus acidoterrestris in apple juice concentrate." in: Journal of food protection, Vol. 69, Issue 5, pp. 1056-60, (2006) (PubMed).

Details zu FHL2

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Andere Bezeichnung: FHL2

Hintergrund: FHL2 is a member of LIM proteins that contain a highly conserved double zinc finger motif called the LIM domain.
Alias Symbols: DRAL, AAG11, FHL-2, SLIM3, SLIM-3
Protein Interaction Partner: SP2, RFX3, REL, NRF1, JUP, INCA1, FAM154A, ZNF417, FAM129A, GLYR1, CCDC92, ARHGAP9, KIAA1217, GNG12, DCP1A, ZFP64, BANP, KANK2, RAI2, ZMYM4, BLZF1, ZNF131, CSN2, SIGLEC6, DTX2, TRIM63, TRIM55, FOXO1, SUMO2, PTCH1, DCTN3, HEXIM1, ERP44, SMAD4, SMAD3, SMAD2
Protein Size: 279

Molekulargewicht: 32 kDa

Gen-ID: 2274

NCBI Accession: NM_201555, NP_963849

UniProt: Q14192

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha