MIER1 Antikörper (Middle Region)

Produktnummer ABIN2775813

Produktdetails anti-MIER1 Antikörper

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MIER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 536 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MIER1

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Andere Bezeichnung: MIER1 (MIER1 Produkte)

Synonyme: 4933425I22Rik antikoerper, 5830411K19Rik antikoerper, mKIAA1610 antikoerper, mier1 antikoerper, wu:fb30a02 antikoerper, zgc:56179 antikoerper, mi-er1 antikoerper, ER1 antikoerper, MI-ER1 antikoerper, RGD1562337 antikoerper, MEIR1 treanscription regulator antikoerper, MIER1 transcriptional regulator antikoerper, mesoderm induction early response 1a, transcriptional regulator antikoerper, mesoderm induction early response 1, transcriptional regulator L homeolog antikoerper, Mier1 antikoerper, MIER1 antikoerper, mier1a antikoerper, mier1.L antikoerper

Hintergrund: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Alias Symbols: ER1, MI-ER1, hMI-ER1, RP5-944N15.1
Protein Interaction Partner: TMEM171, SOX2, HDAC2, HDAC1, EHMT2, CDYL, TUBB1, APP, ELAVL1, UBC, CREBBP, SP1,
Protein Size: 536

Molekulargewicht: 49 kDa

Gen-ID: 57708

NCBI Accession: NM_020948, NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding