MIER1 Antikörper (Middle Region)

Produktnummer ABIN2775813

Der Kaninchen Polyklonal anti-MIER1 Antikörper (ABIN2775813) detektiert spezifisch MIER1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für MIER1 Antikörper (Middle Region) (ABIN2775813)

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MIER1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: MIER1 Antibody - middle region

Sequenz: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MIER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105196

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MIER1

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Andere Bezeichnung: MIER1

Hintergrund:

Background Information: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Gene Name: Mesoderm induction early response 1 homolog (Xenopus laevis)

Alternative Symbols: ER1, MI-ER1

Protein Name: Mesoderm induction early response protein 1

Molekulargewicht: 49kDa

Gen-ID: 57708

NCBI Accession: NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding