RRN3 Antikörper (Middle Region)

Produktnummer ABIN2775808

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RRN3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für RRN3 Antikörper (Middle Region) (ABIN2775808)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RRN3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VDGKVDNGKT KDLYRDLINI FDKLLLPTHA SCHVQFFMFY LCSFKLGFAE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 650 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Andere Bezeichnung: RRN3

Hintergrund: In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.
Alias Symbols: TIFIA, A-270G1.2
Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
Protein Size: 650

Molekulargewicht: 74 kDa

Gen-ID: 54700

NCBI Accession: NM_018427, NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling