CHMP3 Antikörper (N-Term)

Produktnummer ABIN2775802

Dieses Anti-CHMP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHMP3 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für CHMP3 Antikörper (N-Term) (ABIN2775802)

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHMP3 Antikörper

Bindungsspezifität: N-Term

Sequenz: RVVDRQIRDI QREEEKVKRS VKDAAKKGQK DVCIVLAKEM IRSRKAVSKL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against VPS24. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VPS24

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 222 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Andere Bezeichnung: VPS24

Hintergrund: VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.
Alias Symbols: NEDF, VPS24, CGI-149
Protein Interaction Partner: STAMBP, SMAD5, SMAD1, ATP6V1B1, APP, UBD, CHMP4B, CHMP3, CHMP2A, CHMP2B, TNPO3, RAB11A, CHMP4A, VAV2, UBC, VTA1, VPS4A, IGFBP7,
Protein Size: 222

Molekulargewicht: 25 kDa

Gen-ID: 51652

NCBI Accession: NM_016079, NP_057163

UniProt: Q3ZTS9