CBX1 Antikörper (N-Term)
Kurzübersicht für CBX1 Antikörper (N-Term) (ABIN2775787)
Target
Alle CBX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 185 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
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- CBX1 (Chromobox Homolog 1 (CBX1))
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Andere Bezeichnung
- CBX1
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Hintergrund
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CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
Alias Symbols: CBX, HP1-BETA, HP1Hs-beta, M31, MOD1, p25beta, HP1Hsbeta
Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
Protein Size: 185 -
Molekulargewicht
- 21 kDa
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Gen-ID
- 10951
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NCBI Accession
- NM_006807, NP_006798
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UniProt
- P83916
Target
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