PDLIM5 Antikörper (Middle Region)

Produktnummer ABIN2775697

Der Kaninchen Polyklonal Anti-PDLIM5-Antikörper wurde für WB und IHC validiert. Er ist geeignet, PDLIM5 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für PDLIM5 Antikörper (Middle Region) (ABIN2775697)

Target: PDLIM5 (PDZ and LIM Domain 5 (PDLIM5))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDLIM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PDLIM5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VKIPPKRPPR KHIVERYTEF YHVPTHSDAS KKRLIEDTED WRPRTGTTQS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDLIM5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDLIM5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 214 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDLIM5

Target: PDLIM5 (PDZ and LIM Domain 5 (PDLIM5))

Andere Bezeichnung: PDLIM5

Hintergrund: PDLIM5 is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. PDLIM5 is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
Alias Symbols: ENH, ENH1, L9, LIM
Protein Interaction Partner: KRTAP10-7, KRT40, CCDC136, COIL, ZYX, UBC, SUMO2, SUMO3, SUZ12, RNF2, BMI1, PDE12, NPLOC4, IPO11, PLIN3, UBA2, EIF4A3, ANP32A, TPD52, SRP14, RAD23B, PKM, METTL1, CBS, CALU, FN1, ELMSAN1, SIN3A, DSTN, NDUFA7, GFI1B, SUMO1, TRIM39, CACNA1B, PRKCG, PRKCE, PR
Protein Size: 214

Molekulargewicht: 24 kDa

Gen-ID: 10611

NCBI Accession: NM_001011516, NP_001011516

UniProt: Q8WVK0