CCT4 Antikörper (C-Term)

Produktnummer ABIN2775694

Der Kaninchen Polyklonal Anti-CCT4-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CCT4 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für CCT4 Antikörper (C-Term) (ABIN2775694)

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CCT4 Antikörper

Bindungsspezifität: C-Term

Sequenz: AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 539 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CCT4 Antikörper (ABIN2775694)

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Machida, Masutani, Kobayashi, Mikami, Nishino, Miyazawa, Imataka: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." in: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).

Details zu CCT4

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Andere Bezeichnung: CCT4

Hintergrund: The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
Alias Symbols: SRB, Cctd, CCT-DELTA
Protein Interaction Partner: HUWE1, TP53, FUS, CDC20, NEDD1, TUBG1, LGALS3BP, UBC, STAU1, MDM2, RFWD2, VRK2, PRPF40A, CCT7, USP9X, VARS, CCT3, CCT6A, FBXO6, UBD, FBXW4, CDK9, CDK5, CDK2, CD81, IGSF8, HDAC11, HDAC3, RPS6KA1, ILK, ICAM1, PAN2, VCAM1, PPP5C, PEX14, NOS2, US3, FAM86B2, C
Protein Size: 539

Molekulargewicht: 58 kDa

Gen-ID: 10575

NCBI Accession: NM_006430, NP_006421

UniProt: Q53QP9

Pathways: Embryonic Body Morphogenesis