HERC4 Antikörper (N-Term)

Produktnummer ABIN2775668

Produktdetails anti-HERC4 Antikörper

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLCWGNASFG QLGLGGIDEE IVLEPRKSDF FINKRVRDVG CGLRHTVFVL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against HERC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human HERC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 117 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Andere Bezeichnung: HERC4 (HERC4 Produkte)

Synonyme: 1700056O17Rik antikoerper, 4921531D01Rik antikoerper, 9530080M15Rik antikoerper, mKIAA1593 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 4 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 4 S homeolog antikoerper, hect domain and RLD 4 antikoerper, HERC4 antikoerper, herc4 antikoerper, herc4.S antikoerper, Herc4 antikoerper

Hintergrund: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, H2AFV, DCTPP1, C9orf78, NT5C2, FKBP9, NUBP2, USP5, WARS, RAD23A, PCNA, HEXA, HSP90AA1, UBE2J2, UBE2E3, UBE2D2, HERC4, HERC6,
Protein Size: 117

Molekulargewicht: 13 kDa

Gen-ID: 26091

NCBI Accession: NM_015601

UniProt: Q5GLZ8