RAG1 Antikörper (C-Term)

Produktnummer ABIN2775646

Der Kaninchen Polyklonal Anti-RAG1-Antikörper wurde für WB validiert. Er ist geeignet, RAG1 in Proben von Maus, Schwein, Ratte und Pferd zu detektieren.

Kurzübersicht für RAG1 Antikörper (C-Term) (ABIN2775646)

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Reaktivität: Maus, Schwein, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAG1 Antikörper

Bindungsspezifität: C-Term

Sequenz: IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT

Homologie: Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1040 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Andere Bezeichnung: Rag1

Hintergrund: As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Alias Symbols: Rag-1
Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
Protein Size: 1040

Molekulargewicht: 119 kDa

Gen-ID: 19373

NCBI Accession: NM_009019, NP_033045

UniProt: P15919