PATJ Antikörper (N-Term)

Produktnummer ABIN2775641

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-PATJ Antikörper (ABIN2775641) detektiert spezifisch PATJ in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd und Ratte.

Kurzübersicht für PATJ Antikörper (N-Term) (ABIN2775641)

Target: PATJ (INADL) (InaD-Like (INADL))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PATJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PATJ Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PATJ Antibody - N-terminal region

Sequenz: EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against INADL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human INADL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42938-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PATJ Antikörper (ABIN2775641)

Storrs, Silverstein: "PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6." in: Journal of virology, Vol. 81, Issue 8, pp. 4080-90, (2007) (PubMed).

Details zu PATJ

Target: PATJ (INADL) (InaD-Like (INADL))

Andere Bezeichnung: PATJ

Hintergrund:

Background Information: This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.

Gene Name: PATJ, crumbs cell polarity complex component

Alternative Symbols: Cipp, INADL, hINADL, InaD-like

Protein Name: inaD-like protein

Molekulargewicht: 196kDa

Gen-ID: 10207

NCBI Accession: NP_795352

UniProt: Q8NI35