RGS10 Antikörper (N-Term)
Kurzübersicht für RGS10 Antikörper (N-Term) (ABIN2775606)
Target
Alle RGS10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- MFTRAVSRLS RKRPPSDIHD GDGSSSSGHQ SLKSTAKWAS SLENLLEDPE
-
Homologie
- Cow: 93%, Human: 93%, Mouse: 100%, Pig: 93%, Rat: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against Rgs10. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 181 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
-
Andere Bezeichnung
- Rgs10
-
Hintergrund
-
Rgs10 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Rgs10 associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity of Rgs10 on G(z)-alpha is inhibited by palmitoylation of the G-protein.
Alias Symbols: 2310010N19Rik, MGC129414
Protein Size: 181 -
Molekulargewicht
- 21 kDa
-
Gen-ID
- 67865
-
NCBI Accession
- NM_026418, NP_080694
-
UniProt
- Q9CQE5
-
Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
-