RGS7 Antikörper (N-Term)

Produktnummer ABIN2775599

Produktdetails anti-RGS7 Antikörper

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAQGNNYGQT SNGVADESPN MLVYRKMEDV IARMQDEKNG IPIRTVKSFL

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Rgs7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Rgs7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 469 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Andere Bezeichnung: Rgs7 (RGS7 Produkte)

Hintergrund: Rgs7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. It may play an important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations and in synaptic vesicle exocytosis
Protein Interaction Partner: Rgs7bp,
Protein Size: 469

Molekulargewicht: 52 kDa

Gen-ID: 24012

NCBI Accession: NM_011880, NP_036010

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling