DNASE2B Antikörper (Middle Region)

Produktnummer ABIN2775492

Der Kaninchen Polyklonal Anti-DNASE2B-Antikörper wurde für WB validiert. Er ist geeignet, DNASE2B in Proben von Human, Meerschweinchen, Rind (Kuh), Pferd, Ratte und Schwein zu detektieren.

Kurzübersicht für DNASE2B Antikörper (Middle Region) (ABIN2775492)

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reaktivität: Human, Meerschweinchen, Rind (Kuh), Pferd, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DNASE2B Antikörper

Bindungsspezifität: Middle Region

Sequenz: IKAIKLSRHS YFSSYQDHAK WCISQKGTKN RWTCIGDLNR SPHQAFRSGG

Homologie: Cow: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DNASE2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DNASE2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 357 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DNASE2B

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Andere Bezeichnung: DNASE2B

Hintergrund: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: DLAD
Protein Interaction Partner: UBC, UBD,
Protein Size: 357

Molekulargewicht: 39 kDa

Gen-ID: 58511

NCBI Accession: NM_021233, NP_067056

UniProt: Q8WZ79