DNASE2B Antikörper (N-Term)

Produktnummer ABIN405484

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DNASE2B in WB. Es zeigt Reaktivität gegenüber Proben von Human, Meerschweinchen, Ratte, Rind (Kuh), Pferd, Hund und Kaninchen.

Kurzübersicht für DNASE2B Antikörper (N-Term) (ABIN405484)

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reaktivität: Human, Meerschweinchen, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DNASE2B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DNASE2B Antibody - N-terminal region

Sequenz: EGKAVDWFTF YKLPKRQNKE SGETGLEYLY LDSTTRSWRK SEQLMNDTKS

Homologie: Cow: 79%, Dog: 82%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DNASE2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNASE2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42593-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DNASE2B

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Andere Bezeichnung: DNASE2B

Hintergrund:

Background Information: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

Gene Name: Deoxyribonuclease II beta

Alternative Symbols: DLAD

Protein Name: Deoxyribonuclease-2-beta

Molekulargewicht: 39kDa

Gen-ID: 58511

NCBI Accession: NP_067056

UniProt: Q8WZ79