HAO1 Antikörper (C-Term)

Produktnummer ABIN2775438

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HAO1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) und Saccharomyces cerevisiae und wurde in 1 Publikation erwähnt.

Kurzübersicht für HAO1 Antikörper (C-Term) (ABIN2775438)

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HAO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: GLNGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HAO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HAO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 370 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HAO1 Antikörper (ABIN2775438)

Williams, Cregeen, Rumsby: "Identification and expression of a cDNA for human glycolate oxidase." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 246-8, (2000) (PubMed).

Details zu HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Andere Bezeichnung: HAO1

Hintergrund: Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Alias Symbols: GOX, GOX1, HAOX1
Protein Interaction Partner: PEX5, HCVgp1,
Protein Size: 370

Molekulargewicht: 41 kDa

Gen-ID: 54363

NCBI Accession: NM_017545, NP_060015

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process