GTSE1 Antikörper (Middle Region)

Produktnummer ABIN2775434

Produktdetails anti-GTSE1 Antikörper

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTSE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IDLMTNTPDM NKNVAKPSPV VGQLIDLSSP LIQLSPEADK ENVDSPLLKF

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTSE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTSE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 720 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTSE1

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Andere Bezeichnung: GTSE1 (GTSE1 Produkte)

Synonyme: gtse1 antikoerper, MGC81588 antikoerper, MGC89498 antikoerper, GTSE1 antikoerper, fb70b04 antikoerper, fj88g09 antikoerper, wu:fb70b04 antikoerper, wu:fj88g09 antikoerper, wu:fy65d12 antikoerper, MGC114722 antikoerper, B99 antikoerper, Gtse-1 antikoerper, RGD1563164 antikoerper, G2 and S-phase expressed 1 S homeolog antikoerper, G2 and S-phase expressed 1 antikoerper, G-2 and S-phase expressed 1 antikoerper, G2 and S-phase expressed 1 L homeolog antikoerper, G two S phase expressed protein 1 antikoerper, gtse1.S antikoerper, gtse1 antikoerper, GTSE1 antikoerper, gtse1.L antikoerper, Gtse1 antikoerper

Hintergrund: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Alias Symbols: B99
Protein Interaction Partner: UBC, HNRNPD, BARD1, SH3KBP1, SUMO2, USP11,
Protein Size: 720

Molekulargewicht: 76 kDa

Gen-ID: 51512

NCBI Accession: NM_016426, NP_057510

UniProt: Q9NYZ3