GTSE1 Antikörper (N-Term)

Produktnummer ABIN2775433

Der Kaninchen Polyklonal anti-GTSE1 Antikörper (ABIN2775433) detektiert spezifisch GTSE1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein und Kaninchen.

Kurzübersicht für GTSE1 Antikörper (N-Term) (ABIN2775433)

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTSE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GTSE1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GTSE1 Antibody - N-terminal region

Sequenz: NNPVPEQPPL PTSESPFAWS PLAGEKFVEV YKEAHLLALH IESSSRNQAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTSE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTSE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42470-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GTSE1

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Andere Bezeichnung: GTSE1

Hintergrund:

Background Information: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Gene Name: G-2 and S-phase expressed 1

Alternative Symbols: B99

Protein Name: G2 and S phase-expressed protein 1

Molekulargewicht: 76kDa

Gen-ID: 51512

NCBI Accession: NP_057510

UniProt: Q9NYZ3